Potential and beneficial effects of Cinnamomum cassia on gastritis and safety: Literature review and analysis of standard extract

Lee, Ji Hwan; Park, Do Hwi; Lee, Sanghyun; Seo, Hye Jin; Park, Shin Jung; Jung, Kiwon; Kim, Song-Yi; Kang, Ki Sung

doi:10.1186/s13765-021-00661-y

Applied Biological Chemistry

Table 3 Hematological test

From: Potential and beneficial effects of Cinnamomum cassia on gastritis and safety: Literature review and analysis of standard extract

Tests	Units	Hematological test (Recovery groups)
		Groups (mg/kg/day)
		Male		Female
		G1 (DW)	G2 (ECC 1000)	G1 (DW)	G2 (ECC 1000)
RBC	10⁶/μL	6.26 ± 0.50	7.46 ± 0.18	7.48 ± 0.35	6.92 ± 0.21
HGB	g/dL	14.0 ± 1.2	16.3 ± 0.5	16.3 ± 0.5	15.5 ± 0.3
HCT	%	42.6 ± 3.6	50.2 ± 0.2	50.1 ± 1.7	48.5 ± 0.8
MCV	fL	68.1 ± 0.3	67.2 ± 1.3	67.1 ± 0.9	70.1 ± 1.0
MCH	pg	22.3 ± 0.2	21.8 ± 0.1	21.7 ± 0.4	22.5 ± 0.2
MCHC	g/dL	32.8 ± 0.2	32.5 ± 0.8	32.4 ± 0.1	32.0 ± 0.1
RDW	%	13.4 ± 0.2	13.6 ± 0.4	13.8 ± 0.7	13.9 ± 0.4
HDW	g/dL	1.64 ± 0.01	1.71 ± 0.02	1.77 ± 0.28	1.73 ± 0.14
RET	%	0.71 ± 0.15	1.57 ± 0.04	1.71 ± 0.66	1.98 ± 0.84
PLT	10³/μL	237.0 ± 111.7	200.5 ± 24.7	192.0 ± 14.1	229.5 ± 17.7
MPV	fL	11.50 ± 2.12	12.35 ± 0.92	10.20 ± 0.85	11.05 ± 0.35
WBC	10³/μL	7.93 ± 0.73	8.23 ± 0.10	9.39 ± 0.91	7.95 ± 0.40
NEU	%	48.6 ± 9.8	55.2 ± 3.9	54.8 ± 5.7	59.7 ± 0.8
NEU	10³/μL	3.9 ± 1.1	4.5 ± 0.4	5.2 ± 1.0	4.7 ± 0.3
LYM	%	38.9 ± 4.5	35.4 ± 0.9	33.9 ± 3.7	29.8 ± 1.4
LYM	10³/μL	3.1 ± 0.1	2.9 ± 0.0	3.2 ± 0.0	2.4 ± 0.2
MONO	%	9.70 ± 4.10	7.35 ± 2.05	6.65 ± 0.64	7.35 ± 1.48
MONO	10³/μL	0.76 ± 0.25	0.61 ± 0.16	0.62 ± 0.00	0.58 ± 0.08
EOS	%	1.70 ± 0.99	1.55 ± 0.49	4.15 ± 1.20	2.60 ± 0.85
EOS	10³/μL	0.14 ± 0.06	0.13 ± 0.04	0.39 ± 0.08	0.20 ± 0.06
BASO	%	0.85 ± 0.21	0.50 ± 0.28	0.50 ± 0.00	0.35 ± 0.07
BASO	10³/μL	0.07 ± 0.01	0.04 ± 0.03	0.05 ± 0.00	0.03 ± 0.00
LUC	%	0.30 ± 0.14	0.15 ± 0.21	0.15 ± 0.07	0.15 ± 0.07
LUC	10³/μL	0.03 ± 0.01	0.01 ± 0.01	0.02 ± 0.01	0.02 ± 0.01
PT	s	5.9 ± 0.2	6.0 ± 0.1	6.1 ± 0.1	5.8 ± 0.4
APTT	s	13.1 ± 0.8	13.3 ± 0.4	14.9 ± 0.6	13.6 ± 0.3
N		2	2	2	2

Data are expressed as Mean ± S.D
RBC red blood cell, HGB hemoglobin, HCT hematocrit, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, MCHC mean corpuscular hemoglobin con-centratio, RDW red cell distribution width, HDW hemoglobin distribution width, RET reticulocyte, PLT platelet, MPV mean platelet volume, WBC white blood cell, NEU neutrophil, LYM lymphocyte, MONO monocyte, EOS eosinophil, BASO basophil. G1 (DW), G2 (ECC 1000 mg/kg). For statistical analysis, SPSS statistics for medical science 22 (IBM SPSS Statistics, USA), a statistical package widely used commercially, was used, and the significance level was set to p < 0.05

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