Table 1 Human platelet aggregation screening by phytochemicals in Cudrania tricuspidata
From: Artocarpesin acts on human platelet aggregation through inhibition of cyclic nucleotides and MAPKs
Treatment | Aggregation (%) |
|---|---|
Collagen (2.5 μg/mL) | 91.8 ± 1.3 |
Cudraxanthone D | |
40 μM | 91.1 ± 1.1 |
60 μM | 91.2 ± 1.2 |
80 μM | 90.2 ± 1.1 |
100 μM | 92.2 ± 0.5 |
Cudraflavanone B | |
40 μM | 91.0 ± 0.7 |
60 μM | 91.5 ± 0.5 |
80 μM | 89.6 ± 1.2 |
100 μM | 89.4 ± 1.1 |
Alboctalol | |
40 μM | 89.7 ± 1.3 |
60 μM | 90.7 ± 0.8 |
80 μM | 91.3 ± 0.9 |
100 μM | 91.6 ± 1.4 |
Isolupalbigenin | |
40 μM | 92.3 ± 1.5 |
60 μM | 91.7 ± 1.2 |
80 μM | 89.7 ± 1.4 |
100 μM | 90.0 ± 0.8 |
Xanthone V1a | |
40 μM | 88.0 ± 1.5 |
60 μM | 91.0 ± 1.1 |
80 μM | 90.3 ± 1.5 |
100 μM | 92.3 ± 1.4 |
Cudraflavone B | |
40 μM | 91.7 ± 0.5 |
60 μM | 90.0 ± 1.1 |
80 μM | 91.7 ± 1.3 |
100 μM | 92.0 ± 1.5 |
Shuterin | |
40 μM | 90.3 ± 1.5 |
60 μM | 92.1 ± 0.8 |
80 μM | 88.1 ± 1.1 |
100 μM | 90.4 ± 1.2 |
Artocarpesin | |
40 μM | 71.5 ± 1.3 |
60 μM | 44.8 ± 1.0* |
80 μM | 13.0 ± 2.2* |
100 μM | 3.0 ± 0.8** |