Fig. 7
From: CircCEP85 upregulates IGF1 expression to promote breast cancer progression via sponging miR-1193
CircCEP85 promoted BC tumor growth in vivo. A Tumor growth curves in nude mice within 5 weeks; B After 5 weeks, the mice were executed and the tumors were weighed; C Relative expression of ki-67 and IGF1 in xenograft tumor tissues were measured by IHC assay; D The expression levels of circCEP85, miR-1193 and IGF1 in xenograft tumor tissues were detected by qRT-PCR; E The protein levels of IGF1, PCNA, cleaved caspase 3, VEGFA and Naong were evaluated by western blot analysis. ***P < 0.001