Fig. 3From: Crateva unilocularis Buch-Ham leaf extract improves glucose metabolism via regulation of insulin secretion and sensitivity in vitro and in vivoEffect of CULE on cell viability (A), NO production (B), and insulin secretion (C) in cytokine-induced RINm5F pancreatic beta cells. RINm5F pancreatic beta cells were incubated with each concentration of CULE, IL-1β (2 ng/mL) and IFN-γ (100 U/mL) for 48 h. Cell viability was determined by the MTT assay. NO production was determined by a colorimetric assay. L-NAME (1 mM) was used as the positive control. Each value is the mean ± SE of four independent repeated experiments. ###p < 0.001 vs. untreated normal. *p < 0.05, **p < 0.01 vs. controlBack to article page