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Fig. 5 | Applied Biological Chemistry

Fig. 5

From: Isobavachalcone attenuates TNF-α-induced ICAM-1 and VCAM-1 expression in human umbilical vein endothelial cells by regulating the NF-κB signaling pathway

Fig. 5

Isobavachalcone disturbs adhesion of monocytes to HUVEC monolayers. A Monocyte adherence to HUVEC monolayers is represented in the images. HUVECs were incubated with the indicated isobavachalcone (50 µM) and TNF-α (10 ng/mL) for 4 h. Monocytes labeled with a cell tracker were added to the HUVEC monolayer and the degree of adhesion was measured. B Monocyte adhesion to HUVECs was quantified. Bars represent the mean ± SD of three experiments. ***, p < 0.001 vs. CB; ##, p < 0.01 vs. TNF-α

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