Fig. 7
From: Afrormosin exerts an anticancer effect via MAPK and AKT signaling pathways in B16F10 cells
Signaling apoptosis pathway in B16F10 melanoma cells following treatment with afrormosin. Afrormosin modulates the apoptosis signaling pathway in B16F10 cells. A After treatment with afrormosin for 48 h, the expression of the pro-apoptotic protein BAX increased and the expression of the anti-apoptotic protein Bcl-2 decreased. After treatment with afrormosin for 48 h, the expression level of p53 increased and the protein level of procaspase-3 decreased. B The analysis of the protein level by quantitation. *p < 0.05 and **p < 0.01when compared with the control group. The data are presented as the mean ± SD; n = 3