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Applied Biological Chemistry
Fig. 1 | Applied Biological Chemistry

Fig. 1

From: Circular RNA pyridoxal kinase (circPDXK) involves in the progression of ovarian cancer and glycolysis via regulating miR-654-3p and hexokinase II

Fig. 1

The formation and expression of circPDXK. A Schematic diagram showed the back-splicing of exons 2–6 of PDXK. B The existence of circPDXK was detected in the SKOV3 cell line by RT-PCR with convergent or divergent primers and verified using Gel electrophoresis. C–F QPCR estimated relative RNA expression of circPDXK and linear PDXK in C, D RNase R treatment group and mock group, and E, F actinomycin D treatment groups for different durations in SKOV3 and A2780 cells. G, H QPCR estimated relative circPDXK expression in G tumor tissues and adjacent tissues from OVCA cancer patients (n = 52), and H OVCA cell lines (ES-2, OVCAR-3, SKOV3, and A2780) and normal control cell line HOSEpiC. **P < 0.01; ***P < 0.001

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