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Applied Biological Chemistry
Fig. 1 | Applied Biological Chemistry

Fig. 1

From: Effects of SCFAs and TMAO on non-alcoholic fatty liver disease indicating the therapeutic benefits of plant-based diet, and supplemental prebiotics, probiotics and synbiotics

Fig. 1

Beneficial effect of SCFAs on Gut–liver axis. There is a close relationship between the liver and the gut. Humans consume food that is digested and metabolized by microbiota in the gut to produce essential metabolites, such as trimethylamine (TMA), amino acids, and fatty acids, which are transported to the liver via portal veins. Since different microbiota results in distinct products of digestion that will be transported to the liver, healthy gut microbiota is essential for a healthy liver. Diet modification and additives (prebiotics and probiotics) consumption are promising approaches to have a healthy microbiota community. SCFAs are products of the beneficial bacterial community which have various benefits toward the host consisting of improving overall metabolism, strengthening intestinal epithelium, and regulating immune response

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