Skip to main content
Applied Biological Chemistry
Fig. 2 | Applied Biological Chemistry

Fig. 2

From: Effects of SCFAs and TMAO on non-alcoholic fatty liver disease indicating the therapeutic benefits of plant-based diet, and supplemental prebiotics, probiotics and synbiotics

Fig. 2

Dietary modification affects gut and liver health. Dietary modifications and supplementation of additives can improve the gut health by shaping the gut toward a healthy population that produces beneficial metabolites, such as short-chain fatty acids (SCFAs). SCFAs can then be utilized by intestinal cells to produce essential substances, such as lubricating mucus and tight-junction proteins, which are required to maintain the intestinal barrier and proper bowel movement. Meanwhile, excessive intake of red meat containing a high amount of choline and L-carnitine can increase the trimethylamine-N-oxide (TMAO) levels, leading to cardiovascular disease (CVD), non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and cirrhosis

Back to article page