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Applied Biological Chemistry
Fig. 4 | Applied Biological Chemistry

Fig. 4

From: Baicalein facilitates gastric cancer cell apoptosis by triggering endoplasmic reticulum stress via repression of the PI3K/AKT pathway

Fig. 4

Baicalein triggered ERS in GC cells to induce apoptosis by activating BTG3. A, B BTG3 mRNA and protein expression determined by RT-qPCR and Western blot; C Expression levels of Grp78 and CHOP determined by Western blot; D Intracellular Ca2 + levels measured by Fluo-3 AM fluorescent probes; E: Intercellular Ca2 + levels measured by flow cytometry; F: Apoptosis assessed by flow cytometry. Cell experiment was repeated thrice, and the data were showed as mean ± SD. One-way ANOVA was employed for comparisons among multiple groups, followed by Tukey’s test. *p < 0.05, **p < 0.01, ***p < 0.001

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