Mechanism-based biomarkers for the quality control of Dangkwisoo-san: a scoping review

Applied Biological Chemistry

Table 2 Ratio of each herb to Angelicae Gigantis Radix Palva in the Dangkwisoo-san prescription used in the analyzed clinical studies

Study	Disease	Angelicae Gigantis Radix Palva		Linderae Radix		Cyperi Rhizoma		Paeoniae Radix		Sappan Lignum		Carthami Flos		Persicae Semen		Cinnamomi Cortex
Study	Disease	Weight (g)	%	Weight (g)	%	Weight (g)	%	Weight (g)	%	Weight (g)	%	Weight (g)	%	Weight (g)	%	Weight (g)	%
Original prescription^*		6	100	4	67	4	67	4	67	4	67	3.2	53	2.8	47	2.4	40
Wei (2014)	Pulmonary contusion	15	100	12	80	12	80	12	80	9	60	9	60	10	67	6	40
Kim (2021)	Ankle sprain	0.63	100	0.42	67	0.42	67	0.42	67	0.42	67	0.33	52	0.29	46	0.25	40
Huang (2021)	Ankle sprain	0.63	100	0.42	67	0.42	67	0.42	67	0.42	67	0.33	52	0.29	46	0.25	40
NA (1964)	Bruise	5	100	3	60	3	60	3	60	3	60	2	40	3	60	2	40
Chen (1993)	Traumatic pneumothorax	15	100	12	80	12	80	12	80	9	60	9	60	10	67	6	40
Shao (2000)	Peptic ulcer	5	100	3	60	3	60	3	60	3	60	3	60	3	60	2	40

^* The original prescription referred to the Introduction to Medicine written by Li Chan during the Ming Dynasty in China