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Table 4 Summary of ex vivo studies on DS

From: Mechanism-based biomarkers for the quality control of Dangkwisoo-san: a scoping review

Study Target

Experimental model

Inducer

Type of extracts

Concentration

Biomarker and outcome

References

Vasorelaxation

Mouse Aorta

Phenylephrine

Aq

10, 30, 100*, 300* µg/ml

Evaluation of aortic constriction

Kim, J. H. et al. (2011) [25]

Vasorelaxation

New Zealand white rabbit aorta

Phenylephrine

Aq

0.01,0.03,0.1,0.3, 1* mg/ml

Evaluation of aortic constriction

Ko, H. (2019) [52]

  1. * indicates concentrations and biomarkers with statistical significance (p < 0.05) in the article