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Applied Biological Chemistry
Fig. 3 | Applied Biological Chemistry

Fig. 3

From: Paedoksan ameliorates allergic disease through inhibition of the phosphorylation of STAT6 in DNCB-induced atopic dermatitis like mice

Fig. 3

Effects of PDS on 2,4-dinitorchlorobenzene (DNCB)-induced AD-like lesions in the dorsal skin of hairless mice. A Clinical features of PDS treatment (n = 5 in each group). Histopathological features stained by hematoxylin and eosin (H&E) (B) and toluidine blue (C) of dorsal lesions. D Dermatitis score was evaluated by symptoms of lesion such as excoriation/erosion, scarring/dryness, edema, and erythema/hemorrhage. E Level of trans epidermal water loss (TEWL). Measurement of epidermal thickness (F) and infiltration of mast cells (G) in dorsal lesions. The number of infiltrated mast cells in field were counted. Each bar represents the mean ± S.D. (n = 5 in each group). #p < 0.05 vs. control group; *p < 0.05 versus the DNCB group

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