Applied Biological Chemistry

Table 1 Key targets of PDS based on PPI network topological analysis

From: Paedoksan ameliorates allergic disease through inhibition of the phosphorylation of STAT6 in DNCB-induced atopic dermatitis like mice

No.	Uniprot ID	Gene	Degree	Relevance score
1	P05112	IL-4	9	25.38
2	P13501	CCL5	8	15.59
3	P10145	CXCL8	8	17.62
4	P05231	IL-6	7	15.86
5	P01375	TNF	7	24.28
6	P60568	IL-2	5	15.54
7	O00206	TLR4	5	12.89
8	P49682	CXCR3	4	12.54
9	P42226	STAT6	3	11.81
10	P51677	CCR3	2	11.18
11	P06734	FCER2	2	12.32

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