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Applied Biological Chemistry
Fig. 5 | Applied Biological Chemistry

Fig. 5

From: Evaluation of obesity prevention effect of black ginseng on serum, liver, and hypothalamus of mice on a high-fat diet using a metabolomics approach

Fig. 5

A Score and VIP plots of OPLS-DA models created from 57 metabolites detected in the hypo-thalamus of mice. OPLS-DA model represents regression between HFD and HFD + BGEH mice. B Hypothalamus metabolites with VIP values > 1 and p < 0.05 are shown in a normalized graph with unit variance scaling. HFD: high-fat diet; HFD + BGEH: HFD with 600 mg/kg/day black ginseng extract; GABA: 4-aminobutyric acid. *p < 0.05, **p < 0.01 and ***p < 0.001

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