Fig. 7
From: Acute neuro-biochemical changes induced by nitrogen-tungsten co-doped titanium dioxide nanoparticles
Biomarker estimation for assessing oxidative stress in the control group and two treatment groups: NPs T1 and NPs T2, administered with W-N-doped TiO2 NPs at dose of 100 mg/kg and 200 mg/kg respectively, by applying one way ANOVA test a Reactive oxygen species levels depicting a significant dose dependent increase in treatment groups b Nitrite concentration in control and W-N-doped TiO2 NPs treated groups showing a significant concentration dependent increase in treatment groups c Malondialdehyde assay depicting a significant dose dependent increase in treatment groups d Catalase activity assay in control and W-N-doped TiO2 NPs treated groups illustrating a significant dose dependent decrease in both the treatment groups e Super oxide dismutase activity assay showing a significant decrease in treatment groups f Glutathione assay showing a significant dose dependent decrease in treatment groups g Acetylcholinesterase assay in control and W-N-doped TiO2 NPs treated groups showing a significant concentration dependent decrease in both the treatment groups h Dopamine assay showing a significant increase in both the treatment groups i Pro-inflammatory cytokine, Tumor necrosis factor alpha assay in control and W-N-doped TiO2 NPs treated groups showing a significant concentration dependent increase in both the treatment groups j 8-hydroxy 2- deoxyguanoise depicting a significant dose dependent increase in both the treatment groups. p < 0.001