Recent progress on drugs discovery study for treatment of COVID-19: repurposing existing drugs and current natural bioactive molecules

Applied Biological Chemistry

Table 1 General information on some major identified SARS-CoV-2 variants/strains

Variant/strain name	Country origin	First identified	Mutation sites	Refs.
SARS-CoV-2 (Hu-1)	China	December 2019	Wild type	[18, 22, 23]
Alpha (α) B.1.1.7 20I/501Y.V1	United Kingdom	September 2020	N501Y; P681H; 69/70 deletion	[2, 24]
Beta (β) B.1.351 20H/501Y.V2	South Africa	October 2020	K417N; E484K; N501Y	[24]
Gamma (γ) P.1 20 J/501Y.V3	Brazil	November 2020	K417T; E484K; N501Y	[24, 25]
Delta (δ) B.1.617.2	India	December 2020	T19R; L452R; T478K; D614G; P681R; D960N; 157/158 deletion	[26, 27]
Omicron (O) B.1.1.529	Bostwana and South Africa	November 2021	N440K; G446S; G339D; E484A; A76V; Q493R; Q498R; G496S; T547K; Y505H; N679K; H655Y; N764K; N856K; D796Y; Q954H; S375F; L981F; N969K; S371L; L212I; S373P	[28]