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Applied Biological Chemistry
Fig. 4 | Applied Biological Chemistry

Fig. 4

From: Centella asiatica lowers body fat accumulation via regulating cholesterol homeostasis- and lipid metabolism-related genes in mice with high-fat, high-sugar diet-induced obesity

Fig. 4

Microphotographic observation in mice with high-fat, high-sugar diet (HFHSD)-induced obesity that were orally treated with Centella asiatica (CA) for 12 weeks. The liver tissue (A) and epididymal white adipose tissue (eWAT) (B) were stained with hematoxylin and eosin (H&E), and viewed under a microscope (×200) (scale bar = 100 μm). The diameter and macrovesicular area of eWAT (C) were evaluated using ImageJ. Values are the means ± standard error of mean (SEM) for eight mice. The asterisk indicates a significant difference compared to HFHSD (* p < 0.05, *** p < 0.001). NOR, normal diet; HFHSD (Control), HFHSD; CA-L, HFHSD + CA 300 mg/kg; CA-H, HFHSD+CA 600 mg/kg

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