Skip to main content

Table 5 Tissue iron and liver hepcidin levels

From: High-iron consumption decreases copper accumulation and colon length, and alters serum lipids

μg/g

AdFe/LCu#

AdFe/AdCu

AdFe/HCu

HFe/LCu

HFe/AdCu

HFe/HCu

Liver

124.98 ± 21.47

96.64 ± 33.69

80.01 ± 35.20

382.22 ± 71.82

358.47 ± 59.56

352.55 ± 76.81

Liver hepcidin mRNA expression (fold change)

1.11 ± 1.08b

1.00 ± 1.72b

1.04 ± 1.30b

1.25 ± 1.02b

2.71 ± 1.63b

7.14 ± 1.61a

Spleen

0.16 ± 0.02c

0.32 ± 0.07c

1.44 ± 0.45b

0.41 ± 0.21c

1.51 ± 0.24ab

1.69 ± 0.25a

Heart

88.98 ± 10.16ab

80.74 ± 8.88bc

89.28 ± 6.68ab

76.66 ± 13.07c

90.69 ± 8.49ab

100.67 ± 10.91a

Kidney

43.50 ± 4.19 cd

47.04 ± 8.78bc

41.89 ± 7.05 cd

37.46 ± 5.24d

51.72 ± 2.95b

61.64 ± 6.65a

Serum

0.22 ± 0.02

0.22 ± 0.01

0.21 ± 0.02

1.00 ± 0.07

1.15 ± 0.12

1.15 ± 0.12

  1. The results are presented as means ± SDs; n = 10 per individual group. Data were analyzed by two-way ANOVA with Tukey’s post hoc test for further comparisons. Different letters indicate significant differences (P < 0.05) among the labeled means
  2. # H high; Ad adequate; L low