Fig. 5

Oral administration of CLE prevented the loss of spleen and thymus indexes in CPP-induced immunosuppression mice. A The CLE at 50, 100 mg/kg/day was orally administrated in mice for 19 days. Also, the CPP at 80 mg/kg/day was injected on days 17, 18 and 19 to induce immunosuppression. B The body weight of each group was measured. C–E After sacrifice, the organ weight and size of spleen and thymus were measured. ^#p < 0.001 indicates significant differences compared between control group and CPP-injected group. *p < 0.05 indicates a significant differences compared to CPP-injected group