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Applied Biological Chemistry
Fig. 6 | Applied Biological Chemistry

Fig. 6

From: Comprehensive in vitro and in vivo investigations of the therapeutic potential of Jeju lava seawater salt in osteoarthritis

Fig. 6

The effect of Jeju lava seawater (JLS) salt on the pathogenesis of osteoarthritis (OA) in a murine model of DMM-induced OA. Mice in the tap water (TAP, n = 7) and JLS (n = 7) groups underwent DMM surgery, followed by further breading for 8 weeks. a Joint, osteophyte, and cartilage tissue were visualized using Safranin O staining. The OARSI score (b), osteophyte maturity (c), subchondral bone thickness (d), and osteophyte size (e) were quantified. The synovium (f) and synovitis (g) were represented. Statistical analysis was performed using Mann–Whitney U test. Scale bar: 100 μm

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