Fig. 4

Binding pocket interactions from PLIP analysis for NPFF and MiF-1 conjugates as well as the neat peptides. The ligand (conjugate or peptide) is shown in purple. Interacting residues of NOPR are shown in green. (a) NPFF; (b) Gallate-NPFF; (c) Pomolate-NPFF; (d) Betanin-NPFF; (e) Betanin-di-NPFF; (f) Betanin-tri-NPFF; (g) MiF-1; (h) Gallate-MiF-1; (i) Pomolate-MiF1; (j) Betanin-MiF-1; (k) Betanin-di-MiF-1; (l) Betanin-tri-MiF-1 (m) Sinapate-NPFF; (n) Sinapate-MiF1; (o) FGGFTGARKSARKLANQ