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Fig. 4 | Applied Biological Chemistry

Fig. 4

From: Acetyl genistin modulates myotube differentiation and attenuates dexamethasone-induced muscle atrophy through the FoxO1/3 signaling pathway in C2C12 myotubes

Fig. 4

Acetyl genistin inhibits dexamethasone-induced atrophy in C2C12 myotube via AMPK/FoxO-dependent signaling. a Representative images of the western blot analyses for AMPK, FoxO1, and FoxO3 in C2C12 myotubes. b Quantification of the indicated proteins. β-actin was used as a control for protein loading. Data shown are mean ± standard deviation (SD) (n = 3 per group). * p < 0.05, ** p < 0.01, and *** p < 0.001 vs. CTL; ## p < 0.01 and ### p < 0.001 vs. Dexa. CTL control, Dexa dexamethasone, AG acetyl genistin, DAG dexamethasone + acetyl genistin

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