- Short Communication
Trafficking inhibition of bruceanol B as a radical-producing antibiotic
Journal of the Korean Society for Applied Biological Chemistry volume 54, pages 299–301 (2011)
Bruceanol B, isolated from a soil microbe strain DS4, generated oxygen radicals in Bacillus subtilis lysates. Bruceanol B inhibited the trafficking of viral glycoprotein in virus-infected baby hamster kidney (BHK) cells. Bruceanol B also effectively inhibited syncytium formation in a dosedependent manner. However, glycoprotein synthesis was not affected by the compound. Results indicate that bruceanol B generating oxygen radical has inhibitory activity in the trafficking of viral glycoprotein of BHK cell.
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An erratum to this article is available at http://dx.doi.org/10.1007/s13765-012-0026-z.
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Lee, D., Boo, KH., Woo, JK. et al. Trafficking inhibition of bruceanol B as a radical-producing antibiotic. J. Korean Soc. Appl. Biol. Chem. 54, 299–301 (2011). https://doi.org/10.3839/jksabc.2011.047