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  1. Melanoma is a deadly skin cancer with high mortality, and its incidence is increasing every year. Although numerous anticancer drugs have been developed, these treatments have various side effects, such as ski...

    Authors: Huiji Kim, Minjoo Han, Seong-Ah Shin, Jangeun An, Mi-Jeong Ahn, Jun Hyuck Lee, Hyun Ho Park and Chang Sup Lee
    Citation: Applied Biological Chemistry 2022 65:71
    Content type: Article Published on:

  2. The most frequent type of primary liver cancer is hepatocellular carcinoma (HCC), accounting for approximately 90% of primary liver cancers and a third leading cause of cancer deaths. In the current study, the...

    Authors: Farid M. Sroor, Wahid M. Basyouni, Hanan F. Aly, Eman A. Younis, Karima F. Mahrous and Ahmed A. Haroun
    Citation: Applied Biological Chemistry 2022 65:68
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  3. The present study was planned to investigate the possible therapeutic effects of silver/hydroxyapatite nanocomposite (nAg/HAp) on neurotoxicity induced by cadmium chloride (CdCl2) in albino rats. The nanocomposit...

    Authors: Emad Mohamed El-Sherbiny, Eman Ismail Abdel-Gawad and Hala Fawzy Osman
    Citation: Applied Biological Chemistry 2022 65:70
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  4. Phytosterols are important structural components of plant cells that affect membrane fluidity, permeability, and membrane-related metabolic regulation. These compounds, which are abundant in vegetable oils and...

    Authors: Hwan-Hee Bae, Jun Young Ha, Young Sam Go, Jae-Han Son, Beom-Young Son, Jae-Hong Kim, Seonghyu Shin, Tae-Wook Jung and Gibum Yi
    Citation: Applied Biological Chemistry 2022 65:69
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  5. Circ-NT5C2 has been confirmed to be highly expressed and associated to the progression of osteosarcoma (OS). However, the behind mechanism of circ-NT5C2 involvement in OS remains unclear.

    Authors: Xiaoqi Yang, Shuhua Wang, Xianjun Zhang, Xiangbin Gao and Pengfei Xu
    Citation: Applied Biological Chemistry 2022 65:67
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  6. Herbicides play a crucial role in maintaining crop productivity by reducing competition between weeds and crops. Protoporphyrinogen oxidase (PPO)-inhibiting herbicides trigger the photooxidative damage that de...

    Authors: Joon-Yung Cha, Gyeong-Im Shin, Gyeongik Ahn, Song Yi Jeong, Myung Geun Ji, Aliya Alimzhan, Min Gab Kim and Woe-Yeon Kim
    Citation: Applied Biological Chemistry 2022 65:66
    Content type: Article Published on:

  7. Alkyl-4-quinolones (AQs) are natural compounds synthesized by bacteria. Members of this group are known quorum-sensing molecules. Other biological functions, such as anti-bacterial, anti-algal, antifungal, and...

    Authors: Yeo-Jin Park, Gyu‑Sik Choi, Shin-Won Lee and Joong-Hoon Ahn
    Citation: Applied Biological Chemistry 2022 65:65
    Content type: Article Published on:

  8. Colorectal cancer (CRC) is a prevalent malignant tumor with poor prognosis. Circular RNAs (circRNAs) are key regulators in the progression of CRC. Our study aimed to disclose the role of circ_0000554 in CRC.

    Authors: Jinlong Luo, Hua Yang, Xuefeng Peng, Faqiang Zhang, Shilong Shu, Ke Lan, Shengjin Tu, Kai Lu and Xiaoying Cha
    Citation: Applied Biological Chemistry 2022 65:64
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  9. Patients with triple negative breast cancer (TNBC) lack the estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2; thus, conventional hormone and targeted therapies have minima...

    Authors: Ying-Hao Han, Xu-Dong Lian, Seung-Jae Lee, Wei-Long Li, Hu-Nan Sun, Mei-Hua Jin and Taeho Kwon
    Citation: Applied Biological Chemistry 2022 65:63
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  11. Due to the harmful effects of synthetic chemical acaricides on ecosystems and human health, there is increasing interest in the use of nanotechnology to fabricate eco-friendly nanoemulsions based on plant oils...

    Authors: Tamer Ismail, Attia Keratum and Lamia El-Hetawy
    Citation: Applied Biological Chemistry 2022 65:61
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  12. Perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) are persistent organic pollutants (POPs) that are prohibited from being produced and used. However, they remain in the agricultural environ...

    Authors: Geun-Hyoung Choi, Deuk-Yeong Lee, A-Reum Song, Bo-Yeon Moon and Jin-Hyo Kim
    Citation: Applied Biological Chemistry 2022 65:60
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  13. Microorganisms are widely used to produce biologically active substances owing to their versatile ability to convert inexpensive compounds into physiologically active compounds. In this study, we isolated a mi...

    Authors: Ju-Yeong Kang, Won-Jung Park, Youngdae Yoon and Bong-Gyu Kim
    Citation: Applied Biological Chemistry 2022 65:59
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  14. Dysregulated circular RNAs (circRNAs) are implicated in prostate cancer (PCa) progression. Hsa_circ_0081234 (circTRRAP) has been revealed as a facilitator in PCa, but the mechanisms associated with circTRRAP i...

    Authors: Zhihui Li, Yawei Guan, Jingfei Teng, Zhuomin Jia, Guohui Zhang and Xing Ai
    Citation: Applied Biological Chemistry 2022 65:58
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  15. Recent researches indicate the key role of circRNA in gastric cancer (GC) progression. However, the role of circ_0026359 in GC progression remains unclear. This study aims to analyze the role of circ_0026359 i...

    Authors: Shuirong Lu, Jinlai Lu, Lang Liu, Yilong Sun, Yixuan Zhao, Xi Tan and Jingze Li
    Citation: Applied Biological Chemistry 2022 65:57
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  17. Stevia (Stevia rebaudiana Bertoni) is a natural zero calorie sweetener with significant economic and medicinal values due to its high contents of steviosides (SVGs) in the leaves. The aqueous extract of Stevia le...

    Authors: Nagham H. Kamal, Ahmed Essmat, Hesham I. El Askary, Hala M. El Hefnawy, Samia M. Abdel Wahab and Meselhy R. Meselhy
    Citation: Applied Biological Chemistry 2022 65:55
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  18. Herein, two new polymers designated as Cs-EATT and Cs-BATT have been synthesized via linking the chitosan with the synthesized 1,3,4-thiadiazole compounds. They were characterized using 1H,13C-NMR, FT-IR, TGA, El...

    Authors: Ahmad E. Mohamed, Walid E. Elgammal, Aya M. Dawaba, Ahmed G. Ibrahim, Amr Fouda and Saber M. Hassan
    Citation: Applied Biological Chemistry 2022 65:54
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  19. Natural products decursin and decursinol angelate were recently reported as benign fungicides for controlling rice blast. Inspired by the structural similarity of the cumarin compounds and gained hint from the...

    Authors: Yun-Jeong Shin, Jiyoung Shin, Hyewon Jang, Hokyoung Son and Yonghoon Kwon
    Citation: Applied Biological Chemistry 2022 65:53
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  20. Photodynamic therapy (PDT) is a promising cancer treatment with fewer side effects, and it eliminates tumors in target tissues with reactive oxygen species produced by photosensitizers (PS) and light. In this ...

    Authors: Jun Young Ha, Gibum Yi, Hwan Hee Bae, Young Sam Go, Yu Jin Kim, Kwang Min Lee, Chang Oh Hong and Keun Ki Kim
    Citation: Applied Biological Chemistry 2022 65:52
    Content type: Article Published on:

    The Correction to this article has been published in Applied Biological Chemistry 2022 65:62

  21. A sensitive electrochemical sensor for the selective detection of 5ʹ-guanylic acid (5ʹ-GMP) was prepared by combining sulfonated-multiwalled carbon nanotubes (SMWCNTs) and [Ru(bpy)2dpp]Cl2, which were dripped on ...

    Authors: Ying Yu, Siqi Huan, Xiaodan Wang, Cong Yang and Dengyong Liu
    Citation: Applied Biological Chemistry 2022 65:51
    Content type: Article Published on:

  22. Terpenoids are of great interests in a broad range of health-beneficial biological activities and various industrial applications. In plants, terpenoids are synthesized by two distinct pathways, methylerythrit...

    Authors: Min-Kyoung Kang, Ji-Young Kim, Young-Im Choi, Lujie Hu, Chaodong Yang, Zhehao Jin, Yun Ji Park, Soo-Un Kim and Sang-Min Kim
    Citation: Applied Biological Chemistry 2022 65:50
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  23. Increasing evidence demonstrates that circular RNA (circRNA) plays a pivotal role in the development of disease, especially in Cancer. A previous circRNA microarray study showed that circGAK (hsa_circ_0005830)...

    Authors: Hongchun Zhu, Shihong Lv, Baijing Yang, Zhuoxi Liu and Dan Zhang
    Citation: Applied Biological Chemistry 2022 65:48
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  24. Crateva unilocularis Buch-Ham has traditionally been used in Nepal for the treatment and prevention of diabetes. However, scientific verification through studies on the preventive effect of C. unilocularis on dia...

    Authors: Chul-Min Park, Bong-Hwa Jeong, Raj Bhesh Sharma, Hyun-Jung Kim, Dong-Wook Kim and Dong-Young Rhyu
    Citation: Applied Biological Chemistry 2022 65:49
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  25. Fibronectin 1-derived circular RNA hsa_circ_0058092 is a novel potential oncogene in gastric cancer (GC). Yet, previous studies have not determined the role of hsa_circ_0058092 GC progression and the underlyin...

    Authors: Jianming Fang, Jianxin Huang and Xiaodong Zhang
    Citation: Applied Biological Chemistry 2022 65:46
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  26. Vascular inflammation activated by pro-inflammatory cytokines is an inflammatory response that occurs in the early stages of atherosclerosis. Endothelial dysfunction in vascular inflammation begins with the ex...

    Authors: Ae Sin Lee, Jinyoung Hur and Sang Yoon Choi
    Citation: Applied Biological Chemistry 2022 65:45
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  27. Alterations in secondary gut metabolites derived from the microbial fermentation of food in the gut have significant effects on various aspects of host physiology. Our recent studies on obese mice treated with...

    Authors: Dorsilla Anono Katimbwa, Jisun Oh, Chan Ho Jang and Jinkyu Lim
    Citation: Applied Biological Chemistry 2022 65:47
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  28. Increasing evidence has suggested that circular RNAs (circRNAs) play critical roles in breast cancer (BC) progression. However, the expression level and potential functional role of circRNA centrosomal protein...

    Authors: Fei Gao, Jianjun Han, Li Jia, Jun He, Yun Wang and Mi Chen
    Citation: Applied Biological Chemistry 2022 65:44
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  29. Silkworm is an insect that feeds on mulberry leaves only, and silkworm powder has been reported to have antioxidant, hypoglycemic, and anticholesterol activities. In this study, we measured the content of 1-de...

    Authors: Sullim Lee, Quynh Nhu Nguyen, Sung Jin Kim, Joohwan Lee and Myoung-Sook Shin
    Citation: Applied Biological Chemistry 2022 65:43
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  30. Piperine, the major pharmacological ingredient of pepper, can delay the procession of neuropharmacological effects, but its effects and mechanisms on Parkinson's disease dementia (PDD) mice is still unclear, w...

    Authors: Liping Huang, Xiaoqin Zhong, Zhongliu Zhou, Yuanliang Cai and Minzhen Deng
    Citation: Applied Biological Chemistry 2022 65:42
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  31. Diabetes kidney damage (DKD) is a chronic inflammatory disease of the kidney induced with continuous hyperglycemia as the most prevalent consequence of diabetes. Washingtonia filifera seed oil (WFO) was used as a...

    Authors: Mohamed E. El-Beeh, Ashraf A. El-Badawi, Sameer H. Qari, Mohamed Fawzy Ramadan and Wessam M. Filfilan
    Citation: Applied Biological Chemistry 2022 65:41
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  32. Fluorescence spectroscopy, particle size determination, and potential analysis were exploited to elucidate the effect of Lonicera edulis polysaccharide on polyphenol protein. The results revealed that Lonicera ed...

    Authors: Xin Wang, Yu Luo, Rui Ma, Zhili Wang, Shiyou Yu, Chenchen Li and Chunran Han
    Citation: Applied Biological Chemistry 2022 65:40
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  33. This study investigated the distribution and genetic diversity of the indigenous Bradyrhizobium spp. in the Korean agricultural field. A total of 254 Bradyrhizobium strains were isolated from 97 soybean samples (...

    Authors: Ye-eun Kim, Hanseob Shin, Youri Yang and Hor-Gil Hur
    Citation: Applied Biological Chemistry 2022 65:39
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  35. In this study, we performed RNA sequencing of Prx II+/+ and Prx II−/− dermal mesenchymal stem cells (DMSCs) to identify differentially expressed genes (DEGs). To explore the role of Prx II in DMSCs, we performed ...

    Authors: Ying-Hao Han, Ying-Ying Mao, Yao-Yuan Feng, Hong-Yi Xiang, Hu-Nan Sun, Mei-Hua Jin and Taeho Kwon
    Citation: Applied Biological Chemistry 2022 65:37
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  37. The use of eco-friendly methods for the synthesis of nanoparticles and its nano-composite has become a public demand nowadays to reduce the risks of chemical methods. In the current study, green synthesis of C...

    Authors: Aisha M. H. Al-Rajhi, Rana Yahya, Marwah M. Bakri, Reham Yahya and T. M. Abdelghany
    Citation: Applied Biological Chemistry 2022 65:35
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  38. Crude methanol extract (ME) of broccoli (Brassica oleracea L.) sprout was fractioned by hexane, chloroform, ethyl acetate, butanol, and water. The contents of total polyphenols (19.89 mg GAE/g) and flavonoids (10...

    Authors: Ji Soo Kim, Do Manh Cuong, Yu Bin Bae and Somi Kim Cho
    Citation: Applied Biological Chemistry 2022 65:34
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  39. Isoacteoside is a caffeoyl phenylethanoide glycoside found in various plant parts, such as the flower of Magnolia denudata. In particular, magnolia has been studied for its anti-obesity, anticancer, and anti-infl...

    Authors: Chang Geun Choi, Deok Jae Lee, Namhyun Chung and Yong Hoon Joo
    Citation: Applied Biological Chemistry 2022 65:33
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  40. Polycyclic aromatic hydrocarbons (PAHs) are dangerous environmental compounds that are sometimes found in food. The objective of present study was to measure the level of 16 PAHs in bottled water samples (non-...

    Authors: Gholamali Sharifiarab, Abbas Mehraie, Majid Arabameri, Nabi Shariatifar, Amir M. Mortazavian, Mojtaba Moazzen and Sara Sohrabvandi
    Citation: Applied Biological Chemistry 2022 65:32
    Content type: Article Published on:

  42. The gut microbiota plays an important role in the health and disease resistance of the host. Host health depends on the microbiota of the gastrointestinal tract, and imbalance in its composition may leads to c...

    Authors: Abdullah Sheikh, Faisal Almathen and Mohammed Alfattah
    Citation: Applied Biological Chemistry 2022 65:30
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  43. Acanthus ilicifolius var. xiamenensis (Acanthaceae), a mangrove found in southeastern China, is an herb with strong antiinflammatory property. Phytochemical study of the mangrove showed that the plant has a high ...

    Authors: Yifan Zhang, Jinhuang Shen, Xinhua Ma, Mingshuang Yao, Yonghong Zhang and Dairong Cao
    Citation: Applied Biological Chemistry 2022 65:29
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  44. Intrinsic and exogenous signals in conjunction precisely regulate the initiation of flowering. Both signals influence flowering time, which is an integral part of plant reproduction. The signals converge throu...

    Authors: Kihwan Kim, Jooeun Lee, Byeonggyu Kim, Juhyung Shin, Tae-An Kang and Won-Chan Kim
    Citation: Applied Biological Chemistry 2022 65:28
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  45. In this study, we demonstrate that the addition of earthworm castings (EC) in kitchen waste composting reduces ammonia and greenhouse gas (GHG) emissions and improves compost maturity. Kitchen waste (KW) was m...

    Authors: Hyun Young Hwang, Sang Min Lee, Cho Rong Lee and Nan Hee An
    Citation: Applied Biological Chemistry 2022 65:27
    Content type: Article Published on:

  46. In this study, we use high-throughput sequencing-based metagenomic methods to investigate the differences in seasonal structures of the bacterial community and the abundance and diversity of antibiotic resista...

    Authors: Son Giang Nguyen, Shahbaz Raza, Loan Thi Ta, Lan-Anh Thi Le, Cuong Tu Ho and Tatsuya Unno
    Citation: Applied Biological Chemistry 2022 65:26
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  47. The cardiovascular diseases (CVDs) are becoming a critical threat to our lives in these years. It is now widely accepted that platelets play an important role in cardiovascular disease as they have a fundament...

    Authors: Hyuk-Woo Kwon, Muhammad Irfan, Yuan Yee Lee, Man Hee Rhee and Jung-Hae Shin
    Citation: Applied Biological Chemistry 2022 65:25
    Content type: Article Published on:

  48. Being the dietary staple in most Asian countries, the concentrations of toxic and essential element content in rice is an important aspect in terms of both toxicological and nutritional standpoints. This study...

    Authors: Gayani Udeshika Chandrasiri, Kariyawasam Ranaweerage Ranjith Mahanama, Kushani Mahatantila, Pavithra Sajeewani Pitumpe Arachchige and Roshan Chathuranga Midigama Liyanage
    Citation: Applied Biological Chemistry 2022 65:24
    Content type: Article Published on:

  50. In this study, we investigated the effects of dicaffeoylquinic acid derivatives, including 1,4-di-O-caffeoylquinic acid (1,4-DCQA), 3,4-di-O-caffeoylquinic acid (3,4-DCQA), 3,5-di-O-caffeoylquinic acid (3,5-DC...

    Authors: Dahae Lee, Hak-Dong Lee, Hyukjin Kwon, Hye Lim Lee, Gwi Seo Hwang, Sungyeol Choi, Hyun Young Kim, Sanghyun Lee and Ki Sung Kang
    Citation: Applied Biological Chemistry 2022 65:22
    Content type: Article Published on:

    The Correction to this article has been published in Applied Biological Chemistry 2022 65:31

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